BIOTIN FOR PROGRESSIVE MS

Multiple sclerosis is an autoimmune disease in which the immune system attacks the central nervous system. Please see: What is MS.  This includes the brain and the spinal cord. This causes mobility to be compromised and many other symptoms to manifest. Fatigue, loss of bladder function, brain fog and cognitive function are examples of these symptoms.

Studies in recent years suggest that a vital B-vitamin, biotin, might help reduce the impact of the disease. B vitamins are group of vitamins that assist the body with converting food into energy. They support the central nervous system and are vital in maintaining the health of the skin, the eyes, the hair and the liver.

B vitamins are present in a variety of foods that we consume on a daily basis. These include nuts, egg yolks, Swiss chard and other green vegetables as well as liver along with sardines; nuts (almonds, peanuts, pecans, walnuts) as well as cauliflower; bananas; and mushrooms. A more recognized form of B is brewers yeast.

Biotin is also known as vitamin B-7 or vitamin H. It forms one of the B vitamins that we need to optimal body function on a day-to-day basis but the FDA’s recommended dose daily is only 30MCG’s per day. Larger doses have been shown to support the nerve cell metabolism. Myelin is the substance that covers and protects the nerve cells. Biotin activates key enzymes, helping the body to produce more Myelin. Healthy levels of Myelin allow nerve cells to communicate with each other more efficiently. Improvement in the communication between the nerve cells may reduce the level of disability in people with MS and also help protect against further damage.

The main initial study was conducted in France, but further studies have found that high doses of biotin,  can reduce symptoms in people with progressive MS. Additionally people who took these high doses of biotin did not develop any significant adverse reactions. The study can be found here. Other observations noted that eyesight in some patients improved.

An excellent article on the mechanism of how Biotin can help MS can be found here This study discusses the possibility that the lesions of MS may initially be triggered by a deficit of energy metabolism in neutrons that their Mitochondria (the energy powerhouses of cells, which we have discussed before). It highlights how mitochondria in fact may play a key role in different stages of the disease.

It was previously believed that white blood cells (called lymphocytes) were responsible for attacking the body’s own tissue which led to inflammation that was responsible for the demyelination for the protective sheaf surrounding the neuron’s or nerve cells. But it has been discovered that early demyelination can occur in the absence of lymphocytes. Thus it has been determined that the MS might in fact be triggered by hypoxia (lack of oxygen) in neutrons.

 

This new understanding identifies that high dose Biotin can stabilize and even reverse symptoms of progressive MS by restoring energy metabolism and myelin in atrophied neutrons and thus offering Neuro-protective properties.

A Study from October 2018 presented at the 34th Congress of the European Committee for Treatment and Research in Multiple Sclerosis, held October 10-12, 2018, in Berlin, Germany showed positive results.

 

They showed that 300 mg/day, a highly concentrated oral biotin formulation, is effective for reducing disability and improving walking ability in patients with progressive multiple sclerosis (MS).

Personally I have found that Biotin seems to give me more energy and I do think it helps to improve my ability to walk. It also has a positive effect on bladder issues and reduces the urgency to use the bathroom.

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